Evaluation of Left Ventricular Diastolic Function by Echocardiography with Tissue Doppler in Systemic Sclerosis

نویسندگان

  • Marina Carneiro de Freitas Roque
  • Percival D. Sampaio-Barros
  • Ana Lucia Arruda
  • Sergio Barros-Gomes
  • Derly Becker
  • José Lazaro de Andrade
  • Ana Clara Tude Rodrigues
چکیده

BACKGROUND Systemic sclerosis (SS) is a connective tissue abnormality characterized by fibrosis of the skin and internal organs. Cardiac involvement with consequent myocardial dysfunction in SS is associated with increased morbidity and mortality. OBJECTIVE To investigate the left ventricular (LV) diastolic function in patients with SS and preserved systolic function. METHODS Patients with SS were evaluated with two-dimensional echocardiography with tissue Doppler for analysis of chamber diameters, LV mass index (LVMI), indexed left atrial volume (iLAV), systolic function of both ventricles, and presence and degree of diastolic dysfunction (DD). RESULTS We evaluated 50 patients, divided according to the presence of DD into Group 1 (n = 25; normal diastolic function, E/A ratio ≥ 0.8, deceleration time [DT] > 150 ms and < 200 ms, and septal e' > 8 cm/s) and Group 2 (n = 25; with DD, subdivided into type I DD [E/A < 0.8, DT > 200 ms], type II [E/A ≥ 0.8, septal e' < 8 cm/s, iLAV > 34 mL/m2], and type III [E/A > 2, DT < 150 ms, septal e' < 8 cm/s]). Type I DD was the most frequent (34%), followed by type II DD (16%). LVMI and iLAV were similar in both groups, but septal and lateral e' were reduced only in Group 2. In Group 2, we observed that patients with moderate DD had longer disease duration (p = 0.02). CONCLUSION The prevalence of type I DD was elevated in SS and associated with aging. Disease duration emerged as an important factor in moderate DD.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

The influence of Asthma on Right Ventricular Systolic and Diastolic Function in Children according to Tissue Doppler Echocardiography

Introduction:Asthma is the most common chronic inflammatory condition affecting the lower airways among children. Asthma may influence right ventricular (RV) function and patients may develop right ventricular hypertrophy, pulmonary hypertension and cor pulmonale. The main objective of this study is to determine RV dysfunction in asymptomatic asthmatic children as detected by ti...

متن کامل

LEFT VENTRICULAR DIASTOLIC ABNORMALITIES IN β-THALASSEMIA MAJOR WITH NORMAL SYSTOLIC FUNCTION

In order to identify left ventricular diastolic function in patients with betathalassemia major and normal systolic function by noninvasive M-mode and Doppler echocardiography, an analytic study was designed in a university hospital in Sari. We have studied 44 patients (23 men and 21 women), mean age 15.48±2.16 (range 12 to 20) and 43 age and sex matched control subjects. Peak flow velocit...

متن کامل

بررسی اثر کاهش حجم بر روی پارامترهای دیاستولیک اکو کاردیوگرافی در بیماران همودیالیزی

Background: Cardiovascular problems including arterial hypertension, coronary artery diseases, congestive heart failure are prevalent among chronic hemodialyzed patients. Ultrafiltration of hemodialyzed patient's serum, which culminating in intravascular volume reduction, is frequently used during hemodialysis. One of the restrictions of the echocardiographic evaluation of the diastolic heart f...

متن کامل

The Effect of Bronchial Asthma on Interatrial Electromechanical Delay Coupling Obtained Using Tissue Doppler Imaging

Background: Asthma is a predisposing factor for the development of atrial fibrillation. Asthma disturbs the electrophysiology in the right and left atrium. The aim of this study was to evaluate atrial electromechanical delay by coupling obtained from tissue Doppler imaging (TDI) in children. Methods: A cross-sectional study was conducted on 50 patients with Bronchial Asthma, compared with 50 hea...

متن کامل

Non-invasive estimation of cardiac wall stress by using tissue doppler-echocardiography ultrasound images: People with coronary artery stenosis

In this study, a method for non-invasive estimation of stress on the heart wall in  the diastole phase is presented using ultrasound echocardiography and tissue Doppler  imaging. The aim of this study was to evaluate the stress on the heart wall as a  pre-diagnosis  to identify people with coronary artery stenosis. 29 patients with stenosis of more than 70%, 30 patients with stenosis of 50 to 7...

متن کامل

Evaluation of Right Ventricular Function by Tissue Doppler Echocardiography in Asthmatic Children

BackgroundAsthma is the most chronic inflammatory disorder of the airways in children and asthmatic patients can experience cardiac dysfunction, pulmonary hypertension and finally cor pulmonale later in life. We aimed to investigate Right Ventricular (RV) functions in asthmatic children by conventional and tissue Doppler echocardiography (TDE).Materials and Methods Pulmonary function tests, con...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:

دوره 109  شماره 

صفحات  -

تاریخ انتشار 2017